Quantification and Statistical Analysis Methods for Vessel Wall Components from Stained Images with Masson's Trichrome

To develop a digital image processing method to quantify structural components (smooth muscle fibers and extracellular matrix) in the vessel wall stained with Masson's trichrome, and a statistical method suitable for small sample sizes to analyze the results previously obtained. The quantificat...

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Veröffentlicht in:	PloS one 2016-01, Vol.11 (1), p.e0146954-e0146954
Hauptverfasser:	Hernández-Morera, Pablo, Castaño-González, Irene, Travieso-González, Carlos M, Mompeó-Corredera, Blanca, Ortega-Santana, Francisco
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Blood vessels Cluster Analysis Collagen Color Coloring Agents - chemistry Contrast Media Data mining Diagnostic imaging Digital imaging Doctors Electronic Data Processing Extracellular matrix Extracellular Matrix - pathology Feature extraction Health aspects Humans Image processing Image Processing, Computer-Assisted Judgments Medical personnel Methods Morphology Muscle, Smooth - pathology Muscles Normalizing Parallel processing Permutations Physicians Pixels Reproducibility of Results Resampling Saphenous Vein - pathology Smooth muscle Software Staining and Labeling - methods Stains (Microscopy) Statistical analysis Statistical methods Studies Varicose veins Varicose Veins - pathology Venous Insufficiency - physiopathology
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