Texture Analysis of T2-Weighted MR Images to Assess Acute Inflammation in Brain MS Lesions

Brain blood barrier breakdown as assessed by contrast-enhanced (CE) T1-weighted MR imaging is currently the standard radiological marker of inflammatory activity in multiple sclerosis (MS) patients. Our objective was to evaluate the performance of an alternative model assessing the inflammatory acti...

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Veröffentlicht in:	PloS one 2015-12, Vol.10 (12), p.e0145497-e0145497
Hauptverfasser:	Michoux, Nicolas, Guillet, Alain, Rommel, Denis, Mazzamuto, Giosué, Sindic, Christian, Duprez, Thierry
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood-Brain Barrier Brain Brain - diagnostic imaging Brain - pathology Complications and side effects Diagnosis Diffusion Diffusion coefficient Discriminant analysis Humans Image enhancement Inflammation Inflammation - diagnostic imaging Inflammation - pathology Lesions Magnetic resonance imaging Magnetic Resonance Imaging - methods Mathematical models Model accuracy Multiple sclerosis Multiple Sclerosis - diagnostic imaging Multiple Sclerosis - pathology Neuroimaging NMR Nuclear magnetic resonance Parameter identification Parameter sensitivity Patients Pattern Recognition, Automated Radiographic Image Enhancement - methods Regression analysis Risk factors ROC Curve Sequences Statistical analysis Studies Substantia alba Texture
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