In Vitro Evaluation of Spider Silk Meshes as a Potential Biomaterial for Bladder Reconstruction

Reconstruction of the bladder by means of both natural and synthetic materials remains a challenge due to severe adverse effects such as mechanical failure. Here we investigate the application of spider major ampullate gland-derived dragline silk from the Nephila edulis spider, a natural biomaterial...

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Veröffentlicht in:	PloS one 2015-12, Vol.10 (12), p.e0145240-e0145240
Hauptverfasser:	Steins, Anne, Dik, Pieter, Müller, Wally H, Vervoort, Stephin J, Reimers, Kerstin, Kuhbier, Jörn W, Vogt, Peter M, van Apeldoorn, Aart A, Coffer, Paul J, Schepers, Koen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Amino acids Animals Biocompatibility Biology Biomaterials Biomedical materials Bladder Bladder diseases Care and treatment Cell survival Draglines Fibrosis Flow cytometry Gene expression Genes Hospitals Humans Materials Testing Mechanical failure Mechanical properties Medical research Medical schools Mesenchyme Methods Nephila edulis Pediatrics Physiological aspects Plastic surgery Reconstruction Silk Silk - chemistry Spider silk Spiders Stem cells Studies Surgical Mesh Tensile strength Tissue engineering Urinary bladder Urinary Bladder - metabolism Urinary Bladder - pathology Urinary Bladder - surgery Urothelium - metabolism Urothelium - pathology
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