Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals

The Piwi pathway is deeply conserved amongst animals because one of its essential functions is to repress transposons. However, many Piwi-interacting RNAs (piRNAs) do not base-pair to transposons and remain mysterious in their targeting function. The sheer number of piRNA cluster (piC) loci in anima...

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Veröffentlicht in:	PLoS genetics 2015-11, Vol.11 (11), p.e1005652-e1005652
Hauptverfasser:	Chirn, Gung-Wei, Rahman, Reazur, Sytnikova, Yuliya A, Matts, Jessica A, Zeng, Mei, Gerlach, Daniel, Yu, Michael, Berger, Bonnie, Naramura, Mayumi, Kile, Benjamin T, Lau, Nelson C
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biosynthesis Evolution, Molecular Gene expression Genomes Grants Influence Mammals - classification Mammals - genetics Medical research MicroRNA Multigene Family Phylogenetics Phylogeny RNA, Small Interfering - genetics Wildlife conservation
Online-Zugang:	Volltext
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