Label-Free Kinetic Studies of Hemostasis-Related Biomarkers Including D-Dimer Using Autologous Serum Transfusion

The objective of this study was to evaluate the elimination kinetics of hemostasis-related biomarkers including the prothrombin activation fragment F1+2, thrombin-antithrombin complex (TAT), plasmin-α2-antiplasmin complex (PAP), and D-dimer in humans. Autologous serum was used as a biomarker source...

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Veröffentlicht in:	PloS one 2015-12, Vol.10 (12), p.e0145012-e0145012
Hauptverfasser:	Rühl, Heiko, Berens, Christina, Winterhagen, Anna, Müller, Jens, Oldenburg, Johannes, Pötzsch, Bernd
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anticoagulants Antigens Antithrombin Biological markers Biomarkers Biomarkers - blood Blood & organ donations Blood transfusion Blood Transfusion, Autologous Enzyme kinetics Enzymes Female Fibrin Fibrinogen Degradation Products - analysis Fibrinolysis - drug effects Half life Healthy Volunteers Hematology Hemostasis Hemostatics Hepatitis Hospitals Humans Kinetics Life assessment Male Medicine Middle Aged Oligonucleotides Physiological aspects Plasmin Prospective Studies Protein research Prothrombin Radioactive half-life Studies Thrombin Thrombin - analysis Tissue Plasminogen Activator - pharmacology Transfusion Young Adult
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