Newly Developed Sarcopenia as a Prognostic Factor for Survival in Patients who Underwent Liver Transplantation
The relationship between a perioperative change in sarcopenic status and clinical outcome of liver transplantation (LT) is unknown. We investigated whether post-LT sarcopenia and changes in sarcopenic status were associated with the survival of patients. This retrospective study was based on a cohor...
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| Veröffentlicht in: | PloS one 2015-11, Vol.10 (11), p.e0143966-e0143966 |
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| creator | Jeon, Ja Young Wang, Hee-Jung Ock, So Young Xu, Weiguang Lee, Jung-Dong Lee, Jei Hee Kim, Hae Jin Kim, Dae Jung Lee, Kwan Woo Han, Seung Jin |
| description | The relationship between a perioperative change in sarcopenic status and clinical outcome of liver transplantation (LT) is unknown. We investigated whether post-LT sarcopenia and changes in sarcopenic status were associated with the survival of patients.
This retrospective study was based on a cohort of 145 patients from a single transplant center who during a mean of 1 year after LT underwent computed tomography imaging evaluation. The cross-sectional area of the psoas muscle of LT patients was compared with that of age- and sex-matched healthy individuals. The Cox proportional hazards regression model was used to determine whether post-LT sarcopenia and changes in sarcopenic status affect post-LT survival.
The mean age at LT of the 116 male and 29 female patients was 50.2 ± 7.9 years; the mean follow-up duration was 51.6 ± 32.9 months. All pre-LT patients with sarcopenia still had sarcopenia 1 year after LT; 14 (15%) patients had newly developed sarcopenia. The mean survival duration was 91.8 ± 4.2 months for non-sarcopenic patients and 80.0 ± 5.2 months for sarcopenic patients (log-rank test, p = 0.069). In subgroup analysis, newly developed sarcopenia was an independent negative predictor for post-LT survival (hazard ratio: 10.53, 95% confidence interval: 1.37-80.93, p = 0.024).
Sarcopenia in LT recipients did not improve in any of the previously sarcopenic patients and newly developed within 1 year in others. Newly developed sarcopenia was associated with increased mortality. Newly developed sarcopenia can be used to stratify patients with regard to the risk of post-LT mortality. |
| doi_str_mv | 10.1371/journal.pone.0143966 |
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This retrospective study was based on a cohort of 145 patients from a single transplant center who during a mean of 1 year after LT underwent computed tomography imaging evaluation. The cross-sectional area of the psoas muscle of LT patients was compared with that of age- and sex-matched healthy individuals. The Cox proportional hazards regression model was used to determine whether post-LT sarcopenia and changes in sarcopenic status affect post-LT survival.
The mean age at LT of the 116 male and 29 female patients was 50.2 ± 7.9 years; the mean follow-up duration was 51.6 ± 32.9 months. All pre-LT patients with sarcopenia still had sarcopenia 1 year after LT; 14 (15%) patients had newly developed sarcopenia. The mean survival duration was 91.8 ± 4.2 months for non-sarcopenic patients and 80.0 ± 5.2 months for sarcopenic patients (log-rank test, p = 0.069). In subgroup analysis, newly developed sarcopenia was an independent negative predictor for post-LT survival (hazard ratio: 10.53, 95% confidence interval: 1.37-80.93, p = 0.024).
Sarcopenia in LT recipients did not improve in any of the previously sarcopenic patients and newly developed within 1 year in others. Newly developed sarcopenia was associated with increased mortality. Newly developed sarcopenia can be used to stratify patients with regard to the risk of post-LT mortality.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0143966</identifier><identifier>PMID: 26619224</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abdomen ; Adult ; Age ; Body composition ; Body mass index ; Computed tomography ; Confidence intervals ; Diabetes ; Endocrinology ; Female ; Gene expression ; Hazards ; Health aspects ; Hospitals ; Humans ; Life assessment ; Liver ; Liver cancer ; Liver diseases ; Liver Diseases - pathology ; Liver Diseases - physiopathology ; Liver Diseases - therapy ; Liver Transplantation ; Liver transplants ; Male ; Medical imaging ; Medicine ; Metabolism ; Middle Aged ; Mortality ; Muscles ; Musculoskeletal system ; Nutrition ; Patient outcomes ; Patients ; Population ; Prognosis ; Psoas muscle ; Radiography ; Regression Analysis ; Regression models ; Retrospective Studies ; Risk factors ; Sarcopenia ; Sarcopenia - diagnosis ; Sarcopenia - diagnostic imaging ; Sarcopenia - epidemiology ; Statistical analysis ; Subgroups ; Surgery ; Survival ; Survival Analysis ; Tomography ; Transplantation ; Transplants & implants</subject><ispartof>PloS one, 2015-11, Vol.10 (11), p.e0143966-e0143966</ispartof><rights>COPYRIGHT 2015 Public Library of Science</rights><rights>2015 Jeon et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2015 Jeon et al 2015 Jeon et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c758t-da6b9c4884ddf056a669ac46f3d44ee132cda484dd91f6c43a48ff81234ec46c3</citedby><cites>FETCH-LOGICAL-c758t-da6b9c4884ddf056a669ac46f3d44ee132cda484dd91f6c43a48ff81234ec46c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664264/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664264/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79343,79344</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26619224$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Villa, Erica</contributor><creatorcontrib>Jeon, Ja Young</creatorcontrib><creatorcontrib>Wang, Hee-Jung</creatorcontrib><creatorcontrib>Ock, So Young</creatorcontrib><creatorcontrib>Xu, Weiguang</creatorcontrib><creatorcontrib>Lee, Jung-Dong</creatorcontrib><creatorcontrib>Lee, Jei Hee</creatorcontrib><creatorcontrib>Kim, Hae Jin</creatorcontrib><creatorcontrib>Kim, Dae Jung</creatorcontrib><creatorcontrib>Lee, Kwan Woo</creatorcontrib><creatorcontrib>Han, Seung Jin</creatorcontrib><title>Newly Developed Sarcopenia as a Prognostic Factor for Survival in Patients who Underwent Liver Transplantation</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The relationship between a perioperative change in sarcopenic status and clinical outcome of liver transplantation (LT) is unknown. We investigated whether post-LT sarcopenia and changes in sarcopenic status were associated with the survival of patients.
This retrospective study was based on a cohort of 145 patients from a single transplant center who during a mean of 1 year after LT underwent computed tomography imaging evaluation. The cross-sectional area of the psoas muscle of LT patients was compared with that of age- and sex-matched healthy individuals. The Cox proportional hazards regression model was used to determine whether post-LT sarcopenia and changes in sarcopenic status affect post-LT survival.
The mean age at LT of the 116 male and 29 female patients was 50.2 ± 7.9 years; the mean follow-up duration was 51.6 ± 32.9 months. All pre-LT patients with sarcopenia still had sarcopenia 1 year after LT; 14 (15%) patients had newly developed sarcopenia. The mean survival duration was 91.8 ± 4.2 months for non-sarcopenic patients and 80.0 ± 5.2 months for sarcopenic patients (log-rank test, p = 0.069). In subgroup analysis, newly developed sarcopenia was an independent negative predictor for post-LT survival (hazard ratio: 10.53, 95% confidence interval: 1.37-80.93, p = 0.024).
Sarcopenia in LT recipients did not improve in any of the previously sarcopenic patients and newly developed within 1 year in others. Newly developed sarcopenia was associated with increased mortality. Newly developed sarcopenia can be used to stratify patients with regard to the risk of post-LT mortality.</description><subject>Abdomen</subject><subject>Adult</subject><subject>Age</subject><subject>Body composition</subject><subject>Body mass index</subject><subject>Computed tomography</subject><subject>Confidence intervals</subject><subject>Diabetes</subject><subject>Endocrinology</subject><subject>Female</subject><subject>Gene expression</subject><subject>Hazards</subject><subject>Health aspects</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Life assessment</subject><subject>Liver</subject><subject>Liver cancer</subject><subject>Liver diseases</subject><subject>Liver Diseases - pathology</subject><subject>Liver Diseases - physiopathology</subject><subject>Liver Diseases - therapy</subject><subject>Liver Transplantation</subject><subject>Liver transplants</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Metabolism</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Muscles</subject><subject>Musculoskeletal system</subject><subject>Nutrition</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Population</subject><subject>Prognosis</subject><subject>Psoas muscle</subject><subject>Radiography</subject><subject>Regression Analysis</subject><subject>Regression models</subject><subject>Retrospective Studies</subject><subject>Risk factors</subject><subject>Sarcopenia</subject><subject>Sarcopenia - diagnosis</subject><subject>Sarcopenia - diagnostic imaging</subject><subject>Sarcopenia - epidemiology</subject><subject>Statistical analysis</subject><subject>Subgroups</subject><subject>Surgery</subject><subject>Survival</subject><subject>Survival Analysis</subject><subject>Tomography</subject><subject>Transplantation</subject><subject>Transplants & implants</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk11v0zAUhiMEYmPwDxBYQkJw0RJ_xE1ukKbBoFLFJrpxa505duvKtTM7adm_x6XZ1KBdIMvy13Ne-xyfk2WvcT7GdII_rXwXHNhx450a55jRivMn2TGuKBlxktOnB_Oj7EWMqzwvaMn58-yIcI4rQthx5n6orb1DX9RGWd-oGs0hyDRxBhBEBOgy-IXzsTUSnYNsfUA69XkXNmYDFhmHLqE1yrURbZceXbtahW1aopnZqICuArjYWHBtorx7mT3TYKN61Y8n2fX516uz76PZxbfp2elsJCdF2Y5q4DeVZGXJ6lrnBQfOK5CMa1ozphSmRNbAdqcV1lwymhZal5hQphIm6Un2dq_bWB9FH6oo8ISWeU4KNknEdE_UHlaiCWYN4U54MOLvhg8LASF5bZUgnClWqaqUBDPCWJVrzGRFANdJj-qk9bm_rbtZq1om9wPYgejwxJmlWPiNYJyzpJ4EPvQCwd92KrZibaJUNsVN-W7_7hKzosQJffcP-rh3PbWA5IBx2qd75U5UnDLKC16WVZGo8SNUarVaG5nySpu0PzD4ODBITKt-twvoYhTT-c__Zy9-Ddn3B-xSgW2X0dtulzJxCLI9KIOPMSj9EGSci11Z3EdD7MpC9GWRzN4cftCD0X0d0D9DsQiK</recordid><startdate>20151130</startdate><enddate>20151130</enddate><creator>Jeon, Ja Young</creator><creator>Wang, Hee-Jung</creator><creator>Ock, So Young</creator><creator>Xu, Weiguang</creator><creator>Lee, Jung-Dong</creator><creator>Lee, Jei Hee</creator><creator>Kim, Hae Jin</creator><creator>Kim, Dae Jung</creator><creator>Lee, Kwan Woo</creator><creator>Han, Seung Jin</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20151130</creationdate><title>Newly Developed Sarcopenia as a Prognostic Factor for Survival in Patients who Underwent Liver Transplantation</title><author>Jeon, Ja Young ; Wang, Hee-Jung ; Ock, So Young ; Xu, Weiguang ; Lee, Jung-Dong ; Lee, Jei Hee ; Kim, Hae Jin ; Kim, Dae Jung ; Lee, Kwan Woo ; Han, Seung Jin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c758t-da6b9c4884ddf056a669ac46f3d44ee132cda484dd91f6c43a48ff81234ec46c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Abdomen</topic><topic>Adult</topic><topic>Age</topic><topic>Body composition</topic><topic>Body mass index</topic><topic>Computed tomography</topic><topic>Confidence intervals</topic><topic>Diabetes</topic><topic>Endocrinology</topic><topic>Female</topic><topic>Gene expression</topic><topic>Hazards</topic><topic>Health aspects</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Life assessment</topic><topic>Liver</topic><topic>Liver cancer</topic><topic>Liver diseases</topic><topic>Liver Diseases - pathology</topic><topic>Liver Diseases - physiopathology</topic><topic>Liver Diseases - therapy</topic><topic>Liver Transplantation</topic><topic>Liver transplants</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Metabolism</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Muscles</topic><topic>Musculoskeletal system</topic><topic>Nutrition</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Population</topic><topic>Prognosis</topic><topic>Psoas muscle</topic><topic>Radiography</topic><topic>Regression Analysis</topic><topic>Regression models</topic><topic>Retrospective Studies</topic><topic>Risk factors</topic><topic>Sarcopenia</topic><topic>Sarcopenia - diagnosis</topic><topic>Sarcopenia - diagnostic imaging</topic><topic>Sarcopenia - epidemiology</topic><topic>Statistical analysis</topic><topic>Subgroups</topic><topic>Surgery</topic><topic>Survival</topic><topic>Survival Analysis</topic><topic>Tomography</topic><topic>Transplantation</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jeon, Ja Young</creatorcontrib><creatorcontrib>Wang, Hee-Jung</creatorcontrib><creatorcontrib>Ock, So Young</creatorcontrib><creatorcontrib>Xu, Weiguang</creatorcontrib><creatorcontrib>Lee, Jung-Dong</creatorcontrib><creatorcontrib>Lee, Jei Hee</creatorcontrib><creatorcontrib>Kim, Hae Jin</creatorcontrib><creatorcontrib>Kim, Dae Jung</creatorcontrib><creatorcontrib>Lee, Kwan Woo</creatorcontrib><creatorcontrib>Han, Seung Jin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jeon, Ja Young</au><au>Wang, Hee-Jung</au><au>Ock, So Young</au><au>Xu, Weiguang</au><au>Lee, Jung-Dong</au><au>Lee, Jei Hee</au><au>Kim, Hae Jin</au><au>Kim, Dae Jung</au><au>Lee, Kwan Woo</au><au>Han, Seung Jin</au><au>Villa, Erica</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Newly Developed Sarcopenia as a Prognostic Factor for Survival in Patients who Underwent Liver Transplantation</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2015-11-30</date><risdate>2015</risdate><volume>10</volume><issue>11</issue><spage>e0143966</spage><epage>e0143966</epage><pages>e0143966-e0143966</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The relationship between a perioperative change in sarcopenic status and clinical outcome of liver transplantation (LT) is unknown. We investigated whether post-LT sarcopenia and changes in sarcopenic status were associated with the survival of patients.
This retrospective study was based on a cohort of 145 patients from a single transplant center who during a mean of 1 year after LT underwent computed tomography imaging evaluation. The cross-sectional area of the psoas muscle of LT patients was compared with that of age- and sex-matched healthy individuals. The Cox proportional hazards regression model was used to determine whether post-LT sarcopenia and changes in sarcopenic status affect post-LT survival.
The mean age at LT of the 116 male and 29 female patients was 50.2 ± 7.9 years; the mean follow-up duration was 51.6 ± 32.9 months. All pre-LT patients with sarcopenia still had sarcopenia 1 year after LT; 14 (15%) patients had newly developed sarcopenia. The mean survival duration was 91.8 ± 4.2 months for non-sarcopenic patients and 80.0 ± 5.2 months for sarcopenic patients (log-rank test, p = 0.069). In subgroup analysis, newly developed sarcopenia was an independent negative predictor for post-LT survival (hazard ratio: 10.53, 95% confidence interval: 1.37-80.93, p = 0.024).
Sarcopenia in LT recipients did not improve in any of the previously sarcopenic patients and newly developed within 1 year in others. Newly developed sarcopenia was associated with increased mortality. Newly developed sarcopenia can be used to stratify patients with regard to the risk of post-LT mortality.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>26619224</pmid><doi>10.1371/journal.pone.0143966</doi><oa>free_for_read</oa></addata></record> |
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| ispartof | PloS one, 2015-11, Vol.10 (11), p.e0143966-e0143966 |
| issn | 1932-6203 1932-6203 |
| language | eng |
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| source | Public Library of Science (PLoS) Journals Open Access; MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Abdomen Adult Age Body composition Body mass index Computed tomography Confidence intervals Diabetes Endocrinology Female Gene expression Hazards Health aspects Hospitals Humans Life assessment Liver Liver cancer Liver diseases Liver Diseases - pathology Liver Diseases - physiopathology Liver Diseases - therapy Liver Transplantation Liver transplants Male Medical imaging Medicine Metabolism Middle Aged Mortality Muscles Musculoskeletal system Nutrition Patient outcomes Patients Population Prognosis Psoas muscle Radiography Regression Analysis Regression models Retrospective Studies Risk factors Sarcopenia Sarcopenia - diagnosis Sarcopenia - diagnostic imaging Sarcopenia - epidemiology Statistical analysis Subgroups Surgery Survival Survival Analysis Tomography Transplantation Transplants & implants |
| title | Newly Developed Sarcopenia as a Prognostic Factor for Survival in Patients who Underwent Liver Transplantation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T03%3A52%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Newly%20Developed%20Sarcopenia%20as%20a%20Prognostic%20Factor%20for%20Survival%20in%20Patients%20who%20Underwent%20Liver%20Transplantation&rft.jtitle=PloS%20one&rft.au=Jeon,%20Ja%20Young&rft.date=2015-11-30&rft.volume=10&rft.issue=11&rft.spage=e0143966&rft.epage=e0143966&rft.pages=e0143966-e0143966&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0143966&rft_dat=%3Cgale_plos_%3EA436568895%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1738002547&rft_id=info:pmid/26619224&rft_galeid=A436568895&rft_doaj_id=oai_doaj_org_article_264e49e98c21424490f14c92a1d7383f&rfr_iscdi=true |