The Functional SNPs in the 5' Regulatory Region of the Porcine PPARD Gene Have Significant Association with Fat Deposition Traits

Peroxisome proliferator-activated receptor delta (PPARD) is a key regulator of lipid metabolism, insulin sensitivity, cell proliferation and differentiation. In this study, we identified two Single Nucleotide Polymorphisms (SNPs, g.1015 A>G and g.1018 T>C) constituting four haplotypes (GT, GC,...

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Veröffentlicht in:	PloS one 2015-11, Vol.10 (11), p.e0143734-e0143734
Hauptverfasser:	Zhang, Yunxia, Gao, Tengsen, Hu, Shanyao, Lin, Bin, Yan, Dechao, Xu, Zaiyan, Zhang, Zijun, Mao, Yuanliang, Mao, Huimin, Wang, Litong, Wang, Guoshui, Xiong, Yuanzhu, Zuo, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Agriculture Analysis Animal sciences Animals Binding Cell growth Cell Line Cell proliferation Deposition Education Fatty acids Fibroblasts Functional analysis Gene expression Genetics Genotype Genotypes Haplotypes Haplotypes - genetics Hogs Insulin Laboratories Lipid metabolism Lipid Metabolism - genetics Lipids Metabolism Mice Mutation Myoblasts Peroxisome proliferator-activated receptors Peroxisomes Physiological aspects Polymorphism, Single Nucleotide - genetics PPAR delta - genetics Regulatory Sequences, Nucleic Acid - genetics RNA Signal transduction Single nucleotide polymorphisms Single-nucleotide polymorphism Swine Veterinary medicine Zoology
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