M2 Polarization of Monocytes-Macrophages Is a Hallmark of Indian Post Kala-Azar Dermal Leishmaniasis

The high level of functional diversity and plasticity in monocytes/macrophages has been defined within in vitro systems as M1 (classically activated), M2 (alternatively activated) and deactivated macrophages, of which the latter two subtypes are associated with suppression of cell mediated immunity,...

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Veröffentlicht in:	PLoS neglected tropical diseases 2015-10, Vol.9 (10), p.e0004145-e0004145
Hauptverfasser:	Mukhopadhyay, Debanjan, Mukherjee, Shibabrata, Roy, Susmita, Dalton, Jane E, Kundu, Sunanda, Sarkar, Avijit, Das, Nilay K, Kaye, Paul M, Chatterjee, Mitali
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Care and treatment Cell Differentiation Child Councils Cytokines Dendritic cells Development and progression Female Gene Expression Profiling Genotype & phenotype Health care Humans Immunosuppression India Infections Leishmaniasis Leishmaniasis, Cutaneous - immunology Leishmaniasis, Visceral - complications Macrophages Macrophages - immunology Male Medical research Middle Aged Monocytes - immunology Parasites Parasitic diseases Patient outcomes Patients Physiological aspects Studies Wound healing Young Adult
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