Chronic Obstructive Pulmonary Disease-Related Non-Small-Cell Lung Cancer Exhibits a Low Prevalence of EGFR and ALK Driver Mutations

Lung cancer and chronic obstructive pulmonary disease (COPD) are two major lung diseases. Epidermal growth factor receptor (EGFR) mutations, v-Ki-ras2 Kirsten rat sarcoma (KRAS) mutations and anaplastic lymphoma kinase (ALK) gene rearrangements represent driver mutations that are frequently assessed...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2015-11, Vol.10 (11), p.e0142306-e0142306
Hauptverfasser:	Lim, Jeong Uk, Yeo, Chang Dong, Rhee, Chin Kook, Kim, Yong Hyun, Park, Chan Kwon, Kim, Ju Sang, Kim, Jin Woo, Lee, Sang Haak, Kim, Seung Joon, Yoon, Hyoung Kyu, Kim, Tae-Jung, Lee, Kyo Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Air flow Airflow Cancer Carcinoma, Non-Small-Cell Lung - complications Carcinoma, Non-Small-Cell Lung - genetics Chronic obstructive pulmonary disease Confidence intervals Development and progression Diagnosis Disease DNA methylation Epidemiology Epidermal growth factor Epidermal growth factor receptors Female Gene mutations Genetic aspects Genetic Predisposition to Disease Genetic research Genotyping Hospitals Humans Identification and classification Internal medicine K-Ras protein Kinases Lung cancer Lung cancer, Non-small cell Lung diseases Lung diseases, Obstructive Lung Neoplasms - complications Lung Neoplasms - genetics Lymphoma Male Medicine Metastases Middle Aged Molecular modelling Mutation Non-small cell lung carcinoma Obstructive lung disease Pathology Patients Protein-tyrosine kinase Pulmonary Disease, Chronic Obstructive - complications Pulmonary Disease, Chronic Obstructive - genetics Receptor Protein-Tyrosine Kinases - genetics Receptor, Epidermal Growth Factor - genetics Sarcoma Smoking Studies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!