Tir Is Essential for the Recruitment of Tks5 to Enteropathogenic Escherichia coli Pedestals

Enteropathogenic Escherichia coli (EPEC) is a bacterial pathogen that infects the epithelial lining of the small intestine and causes diarrhea. Upon attachment to the intestinal epithelium, EPEC uses a Type III Secretion System to inject its own high affinity receptor Translocated intimin receptor (...

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Veröffentlicht in:	PloS one 2015-11, Vol.10 (11), p.e0141871-e0141871
Hauptverfasser:	Jensen, Helene H, Pedersen, Hans N, Stenkjær, Eva, Pedersen, Gitte A, Login, Frédéric H, Nejsum, Lene N
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actins - chemistry Actins - metabolism Adaptor Proteins, Vesicular Transport - genetics Adaptor Proteins, Vesicular Transport - metabolism Animal migration Animals Bacteria Cell Line Clonal deletion Complications and side effects Diarrhea Dogs E coli Enteropathogenic Escherichia coli - metabolism Epithelial cells Epithelium Escherichia coli Escherichia coli Proteins - metabolism Genes, Reporter Genetic aspects Genetics Infections Intimin Kinases Localization Madin Darby Canine Kidney Cells Mice Microscopy Microscopy, Fluorescence Molecular biology Muscle proteins Pathogens Patient outcomes Phosphorylation Podosomes - metabolism Polymerization Protein Structure, Tertiary Proteins Receptors, Cell Surface - metabolism Secretion Small intestine Time-Lapse Imaging Translocated intimin receptor Wiskott-Aldrich Syndrome Protein, Neuronal - chemistry Wiskott-Aldrich Syndrome Protein, Neuronal - metabolism
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