Human Adipose-Derived Mesenchymal Stem Cells in Cell Therapy: Safety and Feasibility in Different "Hospital Exemption" Clinical Applications

Based on immunomodulatory, osteogenic, and pro-angiogenic properties of adipose-derived stem cells (ASCs), this study aims to assess the safety and efficacy of ASC-derived cell therapies for clinical indications. Two autologous ASC-derived products were proposed to 17 patients who had not experience...

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Veröffentlicht in:	PloS one 2015-10, Vol.10 (10), p.e0139566-e0139566
Hauptverfasser:	Vériter, Sophie, André, Wivine, Aouassar, Najima, Poirel, Hélène Antoine, Lafosse, Aurore, Docquier, Pierre-Louis, Dufrane, Denis
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - transplantation Adolescent Adult Aged Analysis Angiogenesis Autografts Biocompatibility Biomedical materials Bone grafts Bone healing Bone marrow Bone Regeneration - physiology Bone surgery Child Contamination Control stability Feasibility Studies Female Fibroblasts Grafting Growth factors Hospitals Humans Immunomodulation Implantation Life assessment Male Manufacturing Materials handling Mesenchymal Stem Cell Transplantation - adverse effects Mesenchymal Stem Cell Transplantation - methods Mesenchymal stem cells Mesenchymal Stromal Cells Mesenchyme Middle Aged Nonunion Orthopedics Patients Product safety Quality control Quality management Reconstructive Surgical Procedures - methods Safety Skin Stability analysis Stem cell transplantation Stem cells Surgery Surgical implants Surgical instruments Therapeutic applications Therapy Tissue Scaffolds Transplantation Transplantation, Autologous Transplants & implants Wound healing Young Adult
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