Phenotypic and Functional Characterization of Monoclonal Antibodies with Specificity for Rhesus Macaque CD200, CD200R and Mincle

Lectin-like molecules and their receptors are cell surface molecules that have been shown to play a role in either facilitating infection or serving as transporters of HIV/SIV in vivo. The role of these lectin-like molecules in the pathogenesis of HIV/SIV infection continues to be defined. In effort...

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Veröffentlicht in:	PloS one 2015-10, Vol.10 (10), p.e0140689-e0140689
Hauptverfasser:	Byrareddy, Siddappa N, Little, Dawn, Mayne, Ann E, Villinger, Francois, Ansari, Aftab A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Analogs Analysis Animals Antibodies, Monoclonal - immunology Antibodies, Monoclonal - metabolism Antibody Specificity Antigens, CD - immunology Antigens, CD - metabolism Bone marrow Care and treatment CD14 antigen CD16 antigen CD200 antigen Cell surface Cells, Cultured Chemical compounds Chemical properties Colon Dendritic cells Genetic aspects Health aspects HIV HIV infections Human immunodeficiency virus Humans Ileum Immunoglobulins Immunology Infections Laboratories Lectins Lectins, C-Type - immunology Lectins, C-Type - metabolism Leukocytes (mononuclear) Leukocytes, Mononuclear - metabolism Leukocytes, Mononuclear - virology Macaca mulatta Macaca mulatta - immunology Macaca mulatta - metabolism Macrophages Macrophages - metabolism Macrophages - virology Medicine Monoclonal antibodies Pathogenesis Pathology Peripheral blood mononuclear cells Pharmacology Phenotype Physiological aspects Properties Receptors Receptors, Cell Surface - immunology Receptors, Cell Surface - metabolism Simian Acquired Immunodeficiency Syndrome - immunology Simian Immunodeficiency Virus - immunology Tissues U937 Cells Viral infections Viruses
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