Trypanosoma cruzi Binds to Cytokeratin through Conserved Peptide Motifs Found in the Laminin-G-Like Domain of the gp85/Trans-sialidase Proteins

Chagas' disease, caused by the protozoan parasite Trypanosoma cruzi, is a disease that affects millions of people most of them living in South and Central Americas. There are few treatment options for individuals with Chagas' disease making it important to understand the molecular details...

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Veröffentlicht in:	PLoS neglected tropical diseases 2015-09, Vol.9 (9), p.e0004099-e0004099
Hauptverfasser:	Teixeira, Andre Azevedo Reis, de Vasconcelos, Veronica de Cássia Sardinha, Colli, Walter, Alves, Maria Júlia Manso, Giordano, Ricardo José
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs - physiology Binding sites Care and treatment Chagas Disease - metabolism Chagas Disease - parasitology Chagas' disease Chromatography Chromatography, Affinity Conserved Sequence - physiology Distribution Drugs Experiments Glycoproteins Glycoproteins - chemistry Glycoproteins - metabolism Host-Parasite Interactions - physiology Humans Infections Intermediate Filament Proteins - metabolism Keratin Keratins - metabolism Laminin - chemistry Laminin - metabolism Medical research Neuraminidase - chemistry Neuraminidase - metabolism Parasites Peptide bonds Peptides Physiological aspects Protein Binding Protein Structure, Tertiary - physiology Proteins Protozoa Studies Trypanosoma cruzi - metabolism Vimentin - metabolism
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