Electrospun Scaffolds for Osteoblast Cells: Peptide-Induced Concentration-Dependent Improvements of Polycaprolactone

The design of hybrid poly-ε-caprolactone (PCL)-self-assembling peptides (SAPs) matrices represents a simple method for the surface functionalization of synthetic scaffolds, which is essential for cell compatibility. This study investigates the influence of increasing concentrations (2.5%, 5%, 10% an...

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Veröffentlicht in:	PloS one 2015-09, Vol.10 (9), p.e0137505-e0137505
Hauptverfasser:	Dettin, Monica, Zamuner, Annj, Roso, Martina, Gloria, Antonio, Iucci, Giovanna, Messina, Grazia M L, D'Amora, Ugo, Marletta, Giovanni, Modesti, Michele, Castagliuolo, Ignazio, Brun, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amino acids Bioassays Biocompatibility Biological properties Biomedical materials Calcium Calcium - metabolism Cell regulation Cells, Cultured Chemistry Conformation Extracellular matrix Fibers Fourier transforms Gene expression Genetic aspects Growth Humans Hydrogels Industrial engineering Male Materials science Mechanical properties Observations Osteoblasts Osteoblasts - drug effects Osteoblasts - metabolism Peptides Peptides - chemistry Peptides - pharmacology Polycaprolactone Polyesters - chemistry Polyesters - pharmacology Polymers Properties Proteins RNA, Messenger - genetics RNA, Messenger - metabolism SAP protein Scaffolds Surface properties Tissue Scaffolds - chemistry Wettability
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