Microbiological Surveillance of Peritoneal Dialysis Associated Peritonitis: Antimicrobial Susceptibility Profiles of a Referral Center in GERMANY over 32 Years

Microbiological Surveillance of Peritoneal Dialysis Associated Peritonitis: Antimicrobial Susceptibility Profiles of a Referral Center in GERMANY over 32 Years

Peritonitis is one of the most important causes of treatment failure in peritoneal dialysis (PD) patients. This study describes changes in characteristics of causative organisms in PD-related peritonitis and antimicrobial susceptibility. In this single center study we analyzed retrospective 487 susc...

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Veröffentlicht in:PloS one 2015-09, Vol.10 (9), p.e0135969-e0135969
Hauptverfasser: Kitterer, Daniel, Latus, Joerg, Pöhlmann, Christoph, Alscher, M Dominik, Kimmel, Martin
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Acinetobacter
Adult
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Antibiotics
Antiinfectives and antibacterials
Bacteria
Bacterial Infections - drug therapy
Bacterial Infections - epidemiology
Bacterial Infections - microbiology
Cefazolin
Cephalosporins
Dialysis
Drug resistance
Drug Resistance, Microbial
Effluents
Ethics
Female
Gentamicin
Germany - epidemiology
Gram-negative bacteria
Hospitals
Humans
Internal medicine
Kidney diseases
Laboratories
Longitudinal Studies
Male
Medicine
Methicillin
Microbial Sensitivity Tests
Nephrology
Organisms
Patients
Peritoneal dialysis
Peritoneal Dialysis - adverse effects
Peritoneal fluid
Peritoneum
Peritonitis
Peritonitis - drug therapy
Peritonitis - epidemiology
Peritonitis - etiology
Peritonitis - microbiology
Retrospective Studies
Rods
Staphylococcus aureus
Surveillance
Test systems
Vancomycin
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Zusammenfassung:Peritonitis is one of the most important causes of treatment failure in peritoneal dialysis (PD) patients. This study describes changes in characteristics of causative organisms in PD-related peritonitis and antimicrobial susceptibility. In this single center study we analyzed retrospective 487 susceptibility profiles of the peritoneal fluid cultures of 351 adult patients with peritonitis from 1979 to 2014 (divided into three time periods, P1-P3). Staphylococcus aureus decreased from P1 compared to P2 and P3 (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0135969