Comparative Analysis of the Orphan CRISPR2 Locus in 242 Enterococcus faecalis Strains

Clustered, Regularly Interspaced Short Palindromic Repeats and their associated Cas proteins (CRISPR-Cas) provide prokaryotes with a mechanism for defense against mobile genetic elements (MGEs). A CRISPR locus is a molecular memory of MGE encounters. It contains an array of short sequences, called s...

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Veröffentlicht in:	PloS one 2015-09, Vol.10 (9), p.e0138890
Hauptverfasser:	Hullahalli, Karthik, Rodrigues, Marinelle, Schmidt, Brendan D, Li, Xiang, Bhardwaj, Pooja, Palmer, Kelli L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Branches Clustered Regularly Interspaced Short Palindromic Repeats Comparative analysis CRISPR Drug resistance Enterococcus Enterococcus faecalis Enterococcus faecalis - genetics Evolution Evolution, Molecular Gene sequencing Genes Genes, Bacterial Genetic aspects Genetic recombination Genomes Genomics Infections Loci Multilocus Sequence Typing Nucleotide sequence Opportunist infection Phylogenetics Phylogeny Physiological aspects Polymorphism, Single Nucleotide Prokaryotes Proteins Recombination Salmonella Spacer Streptococcus agalactiae
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