Genome-Wide Association Study for Autism Spectrum Disorder in Taiwanese Han Population

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with strong genetic components. Several recent genome-wide association (GWA) studies in Caucasian samples have reported a number of gene regions and loci correlated with the risk of ASD--albeit with very little consensus across studies....

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Veröffentlicht in:	PloS one 2015-09, Vol.10 (9), p.e0138695-e0138695
Hauptverfasser:	Kuo, Po-Hsiu, Chuang, Li-Chung, Su, Mei-Hsin, Chen, Chia-Hsiang, Chen, Chien-Hsiun, Wu, Jer-Yuarn, Yen, Chung-Jen, Wu, Yu-Yu, Liu, Shih-Kai, Chou, Miao-Chun, Chou, Wen-Jiun, Chiu, Yen-Nan, Tsai, Wen-Che, Gau, Susan Shur-Fen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Asian Continental Ancestry Group - genetics Autism Autism Spectrum Disorder - ethnology Autism Spectrum Disorder - genetics Autism Spectrum Disorder - pathology Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics Case-Control Studies Child Child & adolescent psychiatry Child psychology Chromosome Mapping Community colleges Development and progression Disease prevention DNA-Binding Proteins - genetics Empirical analysis Epidemiology Female Gene expression Gene loci Gene mapping Genes Genetic aspects Genetic diversity Genetic susceptibility Genetic variance Genome-wide association studies Genome-Wide Association Study Genomes Genotype Genotyping Glutamate Carboxypeptidase II - genetics Haplotypes Health care Hospitals Humans KRR1 gene Male Mapping Mutation Neurodevelopmental disorders Pathogenesis Pervasive developmental disorders Polymorphism, Single Nucleotide Preventive medicine Public health Receptor Protein-Tyrosine Kinases - genetics Receptors Repressor Proteins - genetics Single-nucleotide polymorphism Studies Taiwan - ethnology Transcription Factors - genetics Young Adult
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