A Genome-Wide mRNA Screen and Functional Analysis Reveal FOXO3 as a Candidate Gene for Chicken Growth

Chicken growth performance provides direct economic benefits to the poultry industry. However, the underlying genetic mechanisms are unclear. The objective of this study was to identify candidate genes associated with chicken growth and investigate their potential mechanisms. We used RNA-Seq to stud...

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Veröffentlicht in:	PloS one 2015-09, Vol.10 (9), p.e0137087-e0137087
Hauptverfasser:	Chen, Biao, Xu, Jiguo, He, Xiaomei, Xu, Haiping, Li, Guihuan, Du, Hongli, Nie, Qinghua, Zhang, Xiquan
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Animal sciences Animals Avian Proteins - genetics Avian Proteins - metabolism Body weight Breast muscle Cell Line Chickens Chickens - genetics Chickens - growth & development Chickens - metabolism DNA methylation Female Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism FOXO3 protein Functional analysis Gene expression Gene Expression Regulation, Developmental Genes Genetics Genome-Wide Association Study Genomes Genomics Growth hormone Insulin-like growth factor II receptors Leg Meat Muscle Proteins - genetics Muscle Proteins - metabolism Muscles Musculoskeletal system MyoD protein Oncorhynchus mykiss Polymorphism, Single Nucleotide Poultry Proteins Quantitative Trait Loci Ribonucleic acid RNA RNA, Messenger - analysis Sequence Analysis, RNA - methods Single-nucleotide polymorphism siRNA Studies Transcription factors Zoology
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