Comparing Effects of Biologic Agents in Treating Patients with Rheumatoid Arthritis: A Multiple Treatment Comparison Regression Analysis

Rheumatoid arthritis patients have been treated with disease modifying anti-rheumatic drugs (DMARDs) and the newer biologic drugs. We sought to compare and rank the biologics with respect to efficacy. We performed a literature search identifying 54 publications encompassing 9 biologics. We conducted...

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Veröffentlicht in:	PloS one 2015-09, Vol.10 (9), p.e0137258-e0137258
Hauptverfasser:	Tvete, Ingunn Fride, Natvig, Bent, Gåsemyr, Jørund, Meland, Nils, Røine, Marianne, Klemp, Marianne
Format:	Artikel
Sprache:	eng
Schlagworte:	Antirheumatic agents Antirheumatic Agents - therapeutic use Arthritis Arthritis, Rheumatoid - drug therapy Autoimmune diseases Biological effects Biological Factors - therapeutic use Clinical trials Complications and side effects Documents Dosage and administration Drug dosages Drug therapy Drugs Etanercept Humans Infliximab Interleukin 1 receptor antagonist Medical research Monoclonal antibodies Patients Probability Ranking Regression Analysis Rheumatoid arthritis Rheumatology Rituximab Tumor necrosis factor-TNF Tumor necrosis factor-α
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