Lack of Dietary Polyunsaturated Fatty Acids Causes Synapse Dysfunction in the Drosophila Visual System

Polyunsaturated fatty acids (PUFAs) are essential nutrients for animals and necessary for the normal functioning of the nervous system. A lack of PUFAs can result from the consumption of a deficient diet or genetic factors, which impact PUFA uptake and metabolism. Both can cause synaptic dysfunction...

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Veröffentlicht in:	PloS one 2015-08, Vol.10 (8), p.e0135353-e0135353
Hauptverfasser:	Ziegler, Anna B, Ménagé, Cindy, Grégoire, Stéphane, Garcia, Thibault, Ferveur, Jean-François, Bretillon, Lionel, Grosjean, Yael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal biology Animals Brain Breeding Diet Dietary Fats - metabolism Dietary Fats - pharmacology Disorders Dose-Response Relationship, Drug Drosophila Drosophila melanogaster Drosophila melanogaster - drug effects Drosophila melanogaster - metabolism Drosophila melanogaster - physiology Electrophysiology Enzymes Essential nutrients Fatty acids Fatty Acids, Unsaturated - metabolism Fatty Acids, Unsaturated - pharmacology Food Gene expression Genetic factors Genetic screening Genetic testing Human health and pathology Insects Life Sciences Lipids Metabolism Molecular chains Molecular modelling Nervous system Neurological diseases Neurophysiology Nutrient deficiency Nutrients Nutritional aspects Omega 6 fatty acids Polyunsaturated fatty acids Rodents Sensory Organs Signal transmission Synapses Synapses - drug effects Synapses - physiology Synaptic transmission Synaptic Transmission - drug effects Unsaturated fatty acids Visual flight Visual perception Visual Perception - drug effects Visual Perception - physiology Visual signals Visual system
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