The Association of Outdoor Activity and Age-Related Cataract in a Rural Population of Taizhou Eye Study: Phase 1 Report

To study the relationship between outdoor activity and risk of age-related cataract (ARC) in a rural population of Taizhou Eye Study (phrase 1 report). A population-based, cross-sectional study of 2006 eligible rural adults (≥45 years old) from Taizhou Eye Study was conducted from Jul. to Sep. 2012....

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Veröffentlicht in:PloS one 2015-08, Vol.10 (8), p.e0135870-e0135870
Hauptverfasser: Tang, Yating, Ji, Yinghong, Ye, Xiaofang, Wang, Xiaofeng, Cai, Lei, Xu, Jianming, Lu, Yi
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container_title PloS one
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creator Tang, Yating
Ji, Yinghong
Ye, Xiaofang
Wang, Xiaofeng
Cai, Lei
Xu, Jianming
Lu, Yi
description To study the relationship between outdoor activity and risk of age-related cataract (ARC) in a rural population of Taizhou Eye Study (phrase 1 report). A population-based, cross-sectional study of 2006 eligible rural adults (≥45 years old) from Taizhou Eye Study was conducted from Jul. to Sep. 2012. Participants underwent detailed ophthalmologic examinations including uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), slit lamp and fundus examinations as well as questionnaires about previous outdoor activity and sunlight protection methods. ARC was recorded by LOCSⅢ classification system. The prevalence of cortical, nuclear and posterior subcapsular cataract were assessed separately for the risk factors and its association with outdoor activity. Of all 2006 eligible participants, 883 (44.0%) adults were diagnosed with ARC. The prevalence rates of cortical, nuclear and posterior subcapsular cataract per person were 41.4%, 30.4% and 1.5%, respectively. Women had a higher tendency of nuclear and cortical cataract than men (OR = 1.559, 95% CI 1.204-2.019 and OR = 1.862, 95% CI 1.456-2.380, respectively). Adults with high myopia had a higher prevalence of nuclear cataract than adults without that (OR = 2.528, 95% CI 1.055-6.062). Multivariable logistic regression revealed that age was risk factor of nuclear (OR = 1.190, 95% CI 1.167-1.213) and cortical (OR = 1.203, 95% CI 1.181-1.226) cataract; eyes with fundus diseases was risk factor of posterior subcapsular cataract (OR = 6.529, 95% CI 2.512-16.970). Outdoor activity was an independent risk factor of cortical cataract (OR = 1.043, 95% CI 1.004-1.083). The risk of cortical cataract increased 4.3% (95% CI 0.4%-8.3%) when outdoor activity time increased every one hour. Furthermore, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year. Outdoor activity was an independent risk factor for cortical cataract, but was not risk factor for nuclear and posterior subcapsular cataract. The risk of cortical cataract increased 4.3% when outdoor activity time increased every one hour. In addition, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year.
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A population-based, cross-sectional study of 2006 eligible rural adults (≥45 years old) from Taizhou Eye Study was conducted from Jul. to Sep. 2012. Participants underwent detailed ophthalmologic examinations including uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), slit lamp and fundus examinations as well as questionnaires about previous outdoor activity and sunlight protection methods. ARC was recorded by LOCSⅢ classification system. The prevalence of cortical, nuclear and posterior subcapsular cataract were assessed separately for the risk factors and its association with outdoor activity. Of all 2006 eligible participants, 883 (44.0%) adults were diagnosed with ARC. The prevalence rates of cortical, nuclear and posterior subcapsular cataract per person were 41.4%, 30.4% and 1.5%, respectively. Women had a higher tendency of nuclear and cortical cataract than men (OR = 1.559, 95% CI 1.204-2.019 and OR = 1.862, 95% CI 1.456-2.380, respectively). Adults with high myopia had a higher prevalence of nuclear cataract than adults without that (OR = 2.528, 95% CI 1.055-6.062). Multivariable logistic regression revealed that age was risk factor of nuclear (OR = 1.190, 95% CI 1.167-1.213) and cortical (OR = 1.203, 95% CI 1.181-1.226) cataract; eyes with fundus diseases was risk factor of posterior subcapsular cataract (OR = 6.529, 95% CI 2.512-16.970). Outdoor activity was an independent risk factor of cortical cataract (OR = 1.043, 95% CI 1.004-1.083). The risk of cortical cataract increased 4.3% (95% CI 0.4%-8.3%) when outdoor activity time increased every one hour. Furthermore, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year. Outdoor activity was an independent risk factor for cortical cataract, but was not risk factor for nuclear and posterior subcapsular cataract. The risk of cortical cataract increased 4.3% when outdoor activity time increased every one hour. In addition, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0135870</identifier><identifier>PMID: 26284359</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acuity ; Adults ; Age ; Aged ; Aged, 80 and over ; Aging - radiation effects ; Cataract - epidemiology ; Cataract - etiology ; Cataracts ; China - epidemiology ; Cortex ; Exposure ; Eye ; Eye (anatomy) ; Female ; Health risk assessment ; Health risks ; Hormone replacement therapy ; Humans ; Intraocular pressure ; Male ; Middle Aged ; Myopia ; Population studies ; Radiation Exposure - adverse effects ; Risk analysis ; Risk Factors ; Rural Population - statistics &amp; numerical data ; Studies ; Surveys ; Ultraviolet radiation ; Ultraviolet Rays - adverse effects ; Visual acuity</subject><ispartof>PloS one, 2015-08, Vol.10 (8), p.e0135870-e0135870</ispartof><rights>COPYRIGHT 2015 Public Library of Science</rights><rights>2015 Tang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2015 Tang et al 2015 Tang et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c758t-35c23482d6f2850e0e4be045588232d6b3e38cf44981514b121ddef4576b53353</citedby><cites>FETCH-LOGICAL-c758t-35c23482d6f2850e0e4be045588232d6b3e38cf44981514b121ddef4576b53353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540437/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540437/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2095,2914,23846,27903,27904,53770,53772,79347,79348</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26284359$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Lin, Haotian</contributor><creatorcontrib>Tang, Yating</creatorcontrib><creatorcontrib>Ji, Yinghong</creatorcontrib><creatorcontrib>Ye, Xiaofang</creatorcontrib><creatorcontrib>Wang, Xiaofeng</creatorcontrib><creatorcontrib>Cai, Lei</creatorcontrib><creatorcontrib>Xu, Jianming</creatorcontrib><creatorcontrib>Lu, Yi</creatorcontrib><title>The Association of Outdoor Activity and Age-Related Cataract in a Rural Population of Taizhou Eye Study: Phase 1 Report</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To study the relationship between outdoor activity and risk of age-related cataract (ARC) in a rural population of Taizhou Eye Study (phrase 1 report). A population-based, cross-sectional study of 2006 eligible rural adults (≥45 years old) from Taizhou Eye Study was conducted from Jul. to Sep. 2012. Participants underwent detailed ophthalmologic examinations including uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), slit lamp and fundus examinations as well as questionnaires about previous outdoor activity and sunlight protection methods. ARC was recorded by LOCSⅢ classification system. The prevalence of cortical, nuclear and posterior subcapsular cataract were assessed separately for the risk factors and its association with outdoor activity. Of all 2006 eligible participants, 883 (44.0%) adults were diagnosed with ARC. The prevalence rates of cortical, nuclear and posterior subcapsular cataract per person were 41.4%, 30.4% and 1.5%, respectively. Women had a higher tendency of nuclear and cortical cataract than men (OR = 1.559, 95% CI 1.204-2.019 and OR = 1.862, 95% CI 1.456-2.380, respectively). Adults with high myopia had a higher prevalence of nuclear cataract than adults without that (OR = 2.528, 95% CI 1.055-6.062). Multivariable logistic regression revealed that age was risk factor of nuclear (OR = 1.190, 95% CI 1.167-1.213) and cortical (OR = 1.203, 95% CI 1.181-1.226) cataract; eyes with fundus diseases was risk factor of posterior subcapsular cataract (OR = 6.529, 95% CI 2.512-16.970). Outdoor activity was an independent risk factor of cortical cataract (OR = 1.043, 95% CI 1.004-1.083). The risk of cortical cataract increased 4.3% (95% CI 0.4%-8.3%) when outdoor activity time increased every one hour. Furthermore, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year. Outdoor activity was an independent risk factor for cortical cataract, but was not risk factor for nuclear and posterior subcapsular cataract. The risk of cortical cataract increased 4.3% when outdoor activity time increased every one hour. In addition, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year.</description><subject>Acuity</subject><subject>Adults</subject><subject>Age</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging - radiation effects</subject><subject>Cataract - epidemiology</subject><subject>Cataract - etiology</subject><subject>Cataracts</subject><subject>China - epidemiology</subject><subject>Cortex</subject><subject>Exposure</subject><subject>Eye</subject><subject>Eye (anatomy)</subject><subject>Female</subject><subject>Health risk assessment</subject><subject>Health risks</subject><subject>Hormone replacement therapy</subject><subject>Humans</subject><subject>Intraocular pressure</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myopia</subject><subject>Population studies</subject><subject>Radiation Exposure - adverse effects</subject><subject>Risk analysis</subject><subject>Risk Factors</subject><subject>Rural Population - statistics &amp; 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A population-based, cross-sectional study of 2006 eligible rural adults (≥45 years old) from Taizhou Eye Study was conducted from Jul. to Sep. 2012. Participants underwent detailed ophthalmologic examinations including uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), slit lamp and fundus examinations as well as questionnaires about previous outdoor activity and sunlight protection methods. ARC was recorded by LOCSⅢ classification system. The prevalence of cortical, nuclear and posterior subcapsular cataract were assessed separately for the risk factors and its association with outdoor activity. Of all 2006 eligible participants, 883 (44.0%) adults were diagnosed with ARC. The prevalence rates of cortical, nuclear and posterior subcapsular cataract per person were 41.4%, 30.4% and 1.5%, respectively. Women had a higher tendency of nuclear and cortical cataract than men (OR = 1.559, 95% CI 1.204-2.019 and OR = 1.862, 95% CI 1.456-2.380, respectively). Adults with high myopia had a higher prevalence of nuclear cataract than adults without that (OR = 2.528, 95% CI 1.055-6.062). Multivariable logistic regression revealed that age was risk factor of nuclear (OR = 1.190, 95% CI 1.167-1.213) and cortical (OR = 1.203, 95% CI 1.181-1.226) cataract; eyes with fundus diseases was risk factor of posterior subcapsular cataract (OR = 6.529, 95% CI 2.512-16.970). Outdoor activity was an independent risk factor of cortical cataract (OR = 1.043, 95% CI 1.004-1.083). The risk of cortical cataract increased 4.3% (95% CI 0.4%-8.3%) when outdoor activity time increased every one hour. Furthermore, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year. Outdoor activity was an independent risk factor for cortical cataract, but was not risk factor for nuclear and posterior subcapsular cataract. The risk of cortical cataract increased 4.3% when outdoor activity time increased every one hour. In addition, the risk of cortical cataract increased 1.1% (95% CI 0.1%-2.0%) when cumulative UV-B exposure time increased every one year.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>26284359</pmid><doi>10.1371/journal.pone.0135870</doi><oa>free_for_read</oa></addata></record>
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source MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry
subjects Acuity
Adults
Age
Aged
Aged, 80 and over
Aging - radiation effects
Cataract - epidemiology
Cataract - etiology
Cataracts
China - epidemiology
Cortex
Exposure
Eye
Eye (anatomy)
Female
Health risk assessment
Health risks
Hormone replacement therapy
Humans
Intraocular pressure
Male
Middle Aged
Myopia
Population studies
Radiation Exposure - adverse effects
Risk analysis
Risk Factors
Rural Population - statistics & numerical data
Studies
Surveys
Ultraviolet radiation
Ultraviolet Rays - adverse effects
Visual acuity
title The Association of Outdoor Activity and Age-Related Cataract in a Rural Population of Taizhou Eye Study: Phase 1 Report
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