Rare Circulating Cells in Familial Waldenström Macroglobulinemia Displaying the MYD88 L265P Mutation Are Enriched by Epstein-Barr Virus Immortalization

The MYD88 L265P is a recurrent somatic mutation in neoplastic cells from patients with Waldenström Macroglobulinemia (WM). We identified the MYD88 L265P mutation in three individuals from unrelated families, but its presence did not explain the disease segregation within these WM pedigrees. We obser...

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Veröffentlicht in:PloS one 2015-09, Vol.10 (9), p.e0136505
Hauptverfasser: Pertesi, Maroulio, Galia, Perrine, Nazaret, Nicolas, Vallée, Maxime, Garderet, Laurent, Leleu, Xavier, Avet-Loiseau, Hervé, Foll, Matthieu, Byrnes, Graham, Lachuer, Joel, McKay, James D, Dumontet, Charles
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Sprache:eng
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