Association of IL10 Polymorphisms and Leprosy: A Meta-Analysis

Leprosy is a chronic infectious disease that depends on the interplay of several factors. Single nucleotide polymorphisms (SNPs) in host immune related genes have been consistently suggested as participants in susceptibility towards disease. Interleukin-10 (IL-10) is a crucial immunomodulatory cytok...

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Veröffentlicht in:	PloS one 2015-09, Vol.10 (9), p.e0136282-e0136282
Hauptverfasser:	Alvarado-Arnez, Lucia Elena, Amaral, Evaldo P, Sales-Marques, Carolinne, Durães, Sandra M B, Cardoso, Cynthia C, Nunes Sarno, Euzenir, Pacheco, Antonio G, Lana, Francisco C F, Moraes, Milton Ozório
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Alleles Analysis Brazil Cytokines Deoxyribonucleic acid Development and progression Disease DNA Female Gene Frequency Genes Genetic aspects Genetic Predisposition to Disease Genomes Haplotypes Humans Immunity, Innate - genetics Immunomodulation Infectious diseases Interleukin 1 Interleukin 10 Interleukin-10 - genetics Interleukin-10 - immunology Leprosy Leprosy - genetics Leprosy - immunology Leprosy - pathology Life assessment Linkage analysis Linkage Disequilibrium Male Medical ethics Meta-analysis Middle Aged Odds Ratio Pathogenesis Patients Physiological aspects Polymorphism Polymorphism, Single Nucleotide Population Populations Promoter Regions, Genetic Single nucleotide polymorphisms Single-nucleotide polymorphism Studies Tuberculosis Tumor necrosis factor-TNF
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