uPAR Expression Pattern in Patients with Urothelial Carcinoma of the Bladder--Possible Clinical Implications

The objective of the present study was to confirm the expression and localisation pattern of the urokinase-type plasminogen activator receptor (uPAR) focusing on its possible clinical relevance in patients with urothelial neoplasia of the bladder. uPAR is a central molecule in tissue remodelling dur...

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Veröffentlicht in:	PloS one 2015-08, Vol.10 (8), p.e0135824-e0135824
Hauptverfasser:	Dohn, Line Hammer, Pappot, Helle, Iversen, Benedikte Richter, Illemann, Martin, Høyer-Hansen, Gunilla, Christensen, Ib Jarle, Thind, Peter, Salling, Lisbeth, von der Maase, Hans, Laerum, Ole Didrik
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens Biomarkers, Tumor - analysis Bladder Bladder cancer Cancer Chemotherapy Cloning Extracellular matrix Female Gene expression Health risks Humans Immunoglobulins Immunohistochemistry Invasiveness Laboratories Lung cancer Macrophages Male Medical prognosis Metastases Metastasis Middle Aged Molecular chains Oncology Paraffin Pathology Patients Position (location) Prostate Receptors, Urokinase Plasminogen Activator - analysis Receptors, Urokinase Plasminogen Activator - metabolism Retrospective Studies Survival Tumors U-Plasminogen activator Urinary Bladder - chemistry Urinary Bladder - pathology Urinary Bladder Neoplasms - chemistry Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology Urokinase Urology Urothelial carcinoma Urothelium - chemistry Urothelium - metabolism Urothelium - pathology
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