Vaccination Drives Changes in Metabolic and Virulence Profiles of Streptococcus pneumoniae

The bacterial pathogen, Streptococcus pneumoniae (the pneumococcus), is a leading cause of life-threatening illness and death worldwide. Available conjugate vaccines target only a small subset (up to 13) of >90 known capsular serotypes of S. pneumoniae and, since their introduction, increases in...

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Veröffentlicht in:	PLoS pathogens 2015-07, Vol.11 (7), p.e1005034-e1005034
Hauptverfasser:	Watkins, Eleanor R, Penman, Bridget S, Lourenço, José, Buckee, Caroline O, Maiden, Martin C J, Gupta, Sunetra
Format:	Artikel
Sprache:	eng
Schlagworte:	Colleges & universities Competition Datasets Funding Host-Pathogen Interactions - immunology Humans Immunology Mathematical models Metabolism Pneumococcal Infections - immunology Pneumococcal Vaccines - immunology Pneumonia Population Serotyping Streptococcus infections Streptococcus pneumoniae - immunology Streptococcus pneumoniae - pathogenicity Vaccination Vaccines Vaccines, Conjugate - immunology Virulence
Online-Zugang:	Volltext
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