Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni

As plans to expand mass drug treatment campaigns to fight schistosomiasis form, worries about reliance on praziquantel as the sole available treatment motivate the investigation for novel antischistosomal compounds. Drug repurposing might be an inexpensive and effective source of novel antischistoso...

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Veröffentlicht in:	PLoS neglected tropical diseases 2015, Vol.9 (7), p.e0003962
Hauptverfasser:	Panic, Gordana, Vargas, Mireille, Scandale, Ivan, Keiser, Jennifer
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemotherapy Disease Drugs FDA approval Female Inhibitory Concentration 50 Libraries Mice Parasitic Sensitivity Tests Pharmaceutical industry Schistosoma mansoni - drug effects Schistosomiasis mansoni - drug therapy Schistosomicides - pharmacology Studies United States United States Food and Drug Administration
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