Reliability of Serum Metabolites over a Two-Year Period: A Targeted Metabolomic Approach in Fasting and Non-Fasting Samples from EPIC

Although metabolic profiles have been associated with chronic disease risk, lack of temporal stability of metabolite levels could limit their use in epidemiological investigations. The present study aims to evaluate the reliability over a two-year period of 158 metabolites and compare reliability ov...

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Veröffentlicht in:	PloS one 2015-08, Vol.10 (8), p.e0135437-e0135437
Hauptverfasser:	Carayol, Marion, Licaj, Idlir, Achaintre, David, Sacerdote, Carlotta, Vineis, Paolo, Key, Timothy J, Onland Moret, N Charlotte, Scalbert, Augustin, Rinaldi, Sabina, Ferrari, Pietro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amines Amino acids Analysis Biogenic amines Cancer Chronic diseases Correlation coefficient Correlation coefficients Disease control Epidemiology Fasting Fasting - blood Female Health risk assessment Health risks Hexoses Humans Male Mass spectrometry Mass spectroscopy Measurement methods Medical disciplines: 700 Medisinske Fag: 700 Metabolites Metabolome Metabolomics Middle Aged Monosaccharides Nutrition Plant lipids Reliability analysis Reproducibility Sampling methods Statistical analysis Statistical methods Studies VDP
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