Overexpression of MMP Family Members Functions as Prognostic Biomarker for Breast Cancer Patients: A Systematic Review and Meta-Analysis

Matrix metalloproteinases (MMPs) are regarded to be relevant to the prognosis of breast cancer. Numerous studies have confirmed the association between MMPs and tumor growth, invasion and metastasis in breast cancer. However, their prognostic values for survival in patients with breast cancer remain...

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Veröffentlicht in:	PloS one 2015-08, Vol.10 (8), p.e0135544-e0135544
Hauptverfasser:	Ren, Fanghui, Tang, Ruixue, Zhang, Xin, Madushi, Wickramaarachchi Mihiranganee, Luo, Dianzhong, Dang, Yiwu, Li, Zuyun, Wei, Kanglai, Chen, Gang
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioindicators Biomarkers Breast cancer Breast Neoplasms - blood Breast Neoplasms - metabolism Breast Neoplasms - pathology Cancer Cancer patients Confidence intervals Female Gelatinase A Gelatinase B Gene Expression Regulation, Neoplastic Health risks Humans Matrix Metalloproteinase 2 - blood Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - blood Matrix Metalloproteinase 9 - metabolism Matrix metalloproteinases Matrix Metalloproteinases - blood Matrix Metalloproteinases - metabolism Medical ethics Medical prognosis Meta-analysis Metastases Metastasis Multivariate analysis Neoplasm Invasiveness Online databases Pathology Patients Prognosis Survival Survival Analysis Systematic review Up-Regulation
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