SNAP23 Regulates Endothelial Exocytosis of von Willebrand Factor

Endothelial exocytosis regulates vascular thrombosis and inflammation. The trafficking and release of endothelial vesicles is mediated by SNARE (Soluble NSF Attachment protein REceptors) molecules, but the exact identity of endothelial SNAREs has been unclear. Three SNARE molecules form a ternary co...

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Veröffentlicht in:	PloS one 2015-08, Vol.10 (8), p.e0118737-e0118737
Hauptverfasser:	Zhu, Qiuyu Martin, Zhu, Qiuyu, Yamakuchi, Munekazu, Lowenstein, Charles J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Cell death Cell Membrane - metabolism Endothelial Cells - metabolism Endothelium Exocytosis Gene Expression Human Umbilical Vein Endothelial Cells Humans Isoforms Laboratory animals Machinery and equipment Medicine Membrane proteins Mice Molecular chains Neurosciences Plasma Polyclonal antibodies Protein Binding Protein Transport Proteins Proteomics Qb-SNARE Proteins - genetics Qb-SNARE Proteins - metabolism Qc-SNARE Proteins - genetics Qc-SNARE Proteins - metabolism Receptors SNAP receptors Syntaxin Thromboembolism Thrombosis Von Willebrand factor von Willebrand Factor - metabolism
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