Structure-Based Phylogenetic Analysis of the Lipocalin Superfamily

Lipocalins constitute a superfamily of extracellular proteins that are found in all three kingdoms of life. Although very divergent in their sequences and functions, they show remarkable similarity in 3-D structures. Lipocalins bind and transport small hydrophobic molecules. Earlier sequence-based p...

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Veröffentlicht in:	PloS one 2015-08, Vol.10 (8), p.e0135507-e0135507
Hauptverfasser:	Lakshmi, Balasubramanian, Mishra, Madhulika, Srinivasan, Narayanaswamy, Archunan, Govindaraju
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Analysis Animal sciences Binding Sites Biochemistry Bioinformatics Biophysics Carrier Proteins - chemistry Carrier Proteins - metabolism Cladistic analysis Clustering Crystallography Evolution Fatty acids Fatty Acids - chemistry Fatty Acids - metabolism Hydrophobicity Ligands Lipocalin Lipocalins - chemistry Lipocalins - classification Lipocalins - genetics Lipocalins - metabolism Models, Molecular Molecular chains Molecular Sequence Data Multigene Family Outliers (statistics) Phylogenetics Phylogeny Protein Binding Protein Conformation Protein families Protein Interaction Domains and Motifs Proteins Quantitative Structure-Activity Relationship Sequence Alignment Similarity Zoology
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