Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women

Preterm birth (PTB) is the leading cause of perinatal mortality worldwide, with the greatest burden occurring in resource-constrained settings. Based on the hypothesis that altered placental angiogenesis and inflammation early in pregnancy lead to PTB, we examined whether levels of inflammatory and...

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Veröffentlicht in:	PloS one 2015-08, Vol.10 (8), p.e0134619-e0134619
Hauptverfasser:	McDonald, Chloe R, Darling, Anne M, Conroy, Andrea L, Tran, Vanessa, Cabrera, Ana, Liles, W Conrad, Wang, Molin, Aboud, Said, Urassa, Willy, Fawzi, Wafaie W, Kain, Kevin C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipokines - blood African Continental Ancestry Group Analysis Angiogenesis Antigens, CD - blood Bioindicators Biomarkers Biomarkers - blood Birth Chemokines Chitinase Chitinase-3-Like Protein 1 Cohort Studies Cytokines Endoglin Enzyme-linked immunosorbent assay Epidemiology Female Gestation Gestational Age Health aspects Health care networks Hospitals Humans Immunology Infant mortality Infant, Newborn Inflammation Intercellular Adhesion Molecule-1 - blood Intercellular Signaling Peptides and Proteins - blood Laboratories Lectins - blood Leptin Leptin - blood Medicine Mortality Multivariate analysis Obstetrics Physiological aspects Placenta Plasma levels Preeclampsia Pregnancy Pregnant women Premature birth Premature Birth - etiology Premature infants Prospective Studies Public health Receptors, Cell Surface - blood Risk Risk reduction Systematic review Tanzania Training Womens health Young Adult
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