Towards Personalized Cardiology: Multi-Scale Modeling of the Failing Heart

Despite modern pharmacotherapy and advanced implantable cardiac devices, overall prognosis and quality of life of HF patients remain poor. This is in part due to insufficient patient stratification and lack of individualized therapy planning, resulting in less effective treatments and a significant...

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Veröffentlicht in:	PloS one 2015-07, Vol.10 (7), p.e0134869-e0134869
Hauptverfasser:	Kayvanpour, Elham, Mansi, Tommaso, Sedaghat-Hamedani, Farbod, Amr, Ali, Neumann, Dominik, Georgescu, Bogdan, Seegerer, Philipp, Kamen, Ali, Haas, Jan, Frese, Karen S, Irawati, Maria, Wirsz, Emil, King, Vanessa, Buss, Sebastian, Mereles, Derliz, Zitron, Edgar, Keller, Andreas, Katus, Hugo A, Comaniciu, Dorin, Meder, Benjamin
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioindicators Biomarkers Biomechanics Cardiology Cardiovascular equipment Disease Electrophysiology Heart Heart diseases Heart failure Heart Failure - pathology Heart Failure - physiopathology Heart Failure - therapy Heart function Hemodynamics Humans Image acquisition Implantation Magnetic resonance Magnetic resonance imaging Mathematical models Medical imaging Medical prognosis Medicine Multi-scale models Multiscale analysis Parameter estimation Patients Pharmacology Phenotyping Precision Medicine Process parameters Prostheses and implants Quality of life Scale models Therapy
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