Co-Expression of TWIST1 and ZEB2 in Oral Squamous Cell Carcinoma Is Associated with Poor Survival

Oral squamous cell carcinoma (OSCC) is an aggressive disease accounting for more than 260,000 cancer cases diagnosed and 128,000 deaths worldwide. A large majority of cancer deaths result from cancers that have metastasized beyond the primary tumor. The relationship between genetic changes and clini...

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Veröffentlicht in:	PloS one 2015-07, Vol.10 (7), p.e0134045-e0134045
Hauptverfasser:	Kong, Yink Heay, Syed Zanaruddin, Sharifah Nurain, Lau, Shin Hin, Ramanathan, Anand, Kallarakkal, Thomas George, Vincent-Chong, Vui King, Wan Mustafa, Wan Mahadzir, Abraham, Mannil Thomas, Abdul Rahman, Zainal Ariff, Zain, Rosnah Binti, Cheong, Sok Ching
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis Bioindicators Biomarkers Biomarkers, Tumor - biosynthesis Cancer Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - therapy Cell adhesion & migration Cell survival Correlation analysis Dentistry Diagnosis Diagnostic systems Disease-Free Survival E-cadherin Esophagus Fatalities Female Gene expression Gene Expression Regulation, Neoplastic Homeodomain Proteins - biosynthesis Humans Humic acids Immunohistochemistry Invasiveness Lymph nodes Lymphatic Metastasis Lymphatic system Male Maxillofacial surgery Medical prognosis Medical research Mesenchyme Metastases Metastasis Middle Aged Mouth Neoplasms - metabolism Mouth Neoplasms - mortality Mouth Neoplasms - pathology Mouth Neoplasms - therapy Mucosa Neoplasm Proteins - biosynthesis Nuclear Proteins - biosynthesis Oral cancer Oral squamous cell carcinoma Patient outcomes Patients Proteins Repressor Proteins - biosynthesis Snail protein Squamous cell carcinoma Stem cells Studies Surgery Survival Survival Rate Tissues Transcription factors Tumors Twist-Related Protein 1 - biosynthesis Zinc Finger E-box Binding Homeobox 2
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