Epinephrine Activation of the β2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells

Mucus hypersecretion by airway epithelium is a hallmark of inflammation in allergic asthma and results in airway narrowing and obstruction. Others have shown that administration a TH2 cytokine, IL-13 is sufficient to cause mucus hypersecretion in vivo and in vitro. Asthma therapy often utilizes β2-a...

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Veröffentlicht in:PloS one 2015-07, Vol.10 (7), p.e0132559-e0132559
Hauptverfasser: Al-Sawalha, Nour, Pokkunuri, Indira, Omoluabi, Ozozoma, Kim, Hosu, Thanawala, Vaidehi J, Hernandez, Adrian, Bond, Richard A, Knoll, Brian J
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Sprache:eng
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