Gold Nanoparticle-Photosensitizer Conjugate Based Photodynamic Inactivation of Biofilm Producing Cells: Potential for Treatment of C. albicans Infection in BALB/c Mice

Photodynamic therapy (PDT) has been found to be effective in inhibiting biofilm producing organisms. We investigated the photodynamic effect of gold nanoparticle (GNP) conjugated photosensitizers against Candida albicans biofilm. We also examined the photodynamic efficacy of photosensitizer (PS) con...

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Veröffentlicht in:	PloS one 2015-07, Vol.10 (7), p.e0131684-e0131684
Hauptverfasser:	Sherwani, Mohd Asif, Tufail, Saba, Khan, Aijaz Ahmed, Owais, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Aloe vera Animals Biofilms Biofilms - drug effects Biotechnology Candida Candida albicans Candida albicans - drug effects Catheters Conjugates Conjugation Deactivation Effectiveness Female Fungal infections Gold Gold - pharmacology Inactivation Infections Interdisciplinary aspects Metal Nanoparticles - administration & dosage Methylene blue Methylene Blue - pharmacology Mice Mice, Inbred BALB C Nanoparticles Photochemotherapy - methods Photodynamic therapy Photosensitizing Agents - pharmacology Planktonic cells Skin Surgical implants Synergism Tolonium Chloride - pharmacology Toluidine Toluidine blue
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