Effects of Endocrine Disruptor Compounds, Alone or in Combination, on Human Macrophage-Like THP-1 Cell Response

The aim of the present study was to evaluate the immunological effects on human macrophages of four endocrine disruptor compounds (EDCs) using the differentiated human THP-1 cell line as a model. We studied first the effects of these EDCs, including Bisphenol A (BPA), di-ethylhexyl-phthalate (DEHP),...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2015-07, Vol.10 (7), p.e0131428-e0131428
Hauptverfasser:	Couleau, N, Falla, J, Beillerot, A, Battaglia, E, D'Innocenzo, M, Plançon, S, Laval-Gilly, P, Bennasroune, A
Format:	Artikel
Sprache:	eng
Schlagworte:	4-tert-Octylphenol Benzhydryl Compounds - pharmacology Bisphenol A Cell Line Combined treatment Cytokines Dibutyl phthalate Dibutyl Phthalate - pharmacology Diethylhexyl Phthalate - pharmacology Dioctyl phthalate Dose-Response Relationship, Drug Endocrine disruptors Endocrine Disruptors - pharmacology Estrogen receptors Estrogens Gene Expression Regulation Human behavior Humans Immune response Immune system Immunology Interleukin 1 Interleukin 8 Interleukin-1beta - agonists Interleukin-1beta - metabolism Interleukin-8 - agonists Interleukin-8 - metabolism Kinases Life Sciences Low concentrations Macrophages Macrophages - cytology Macrophages - drug effects Macrophages - metabolism MAP kinase Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors Mitogen-Activated Protein Kinase 1 - genetics Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors Mitogen-Activated Protein Kinase 3 - genetics Mitogen-Activated Protein Kinase 3 - metabolism Pesticides Phagocytosis Phagocytosis - drug effects Phenols Phenols - pharmacology Phosphorylation Phosphorylation - drug effects Receptors Receptors, Estrogen - genetics Receptors, Estrogen - metabolism Secretions Signal Transduction Toxicology Tumor Necrosis Factor-alpha - agonists Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-α Zebrafish
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!