Oncocalyxone A functions as an anti-glycation agent in vitro

Advanced glycation endproducts (AGE) are the result of post-translational changes to proteins, which ultimately compromise their structure and/or function. The identification of methods to prevent the formation of these compounds holds great promise in the development of alternative therapies for di...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6), p.e0131222-e0131222
Hauptverfasser:	Melo, Ingrid Sofia Vieira de, Santos, Aldenir Feitosa Dos, Lemos, Telma Leda Gomes de, Goulart, Marília Oliveira Fonseca, Santana, Antônio Euzébio Goulart
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced glycosylation end products Age Alzheimer's disease Analgesics Animals Anthraquinones - chemistry Anthraquinones - pharmacology Antioxidants Brazil Cattle Chemistry Diabetes Diabetes mellitus Diabetes therapy Dose-Response Relationship, Drug Drug Evaluation, Preclinical Enzymes Fructose - chemistry Glucose - chemistry Glycation End Products, Advanced - chemistry Glycosylation Identification methods Inhibitory Concentration 50 Medical treatment Medicinal plants Medicine, Traditional Oxidative stress Pharmaceutical sciences Plant Extracts - chemistry Post-translation Proteins Serum Albumin, Bovine - chemistry Spectrometry, Fluorescence Structure-function relationships
Online-Zugang:	Volltext
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