Mortality in Children with Optic Pathway Glioma Treated with Up-Front BB-SFOP Chemotherapy

In terms of overall survival (OS), limited data are available for the very long-term outcomes of children treated for optic pathway glioma (OPG) with up-front chemotherapy. Therefore, we undertook this study with the aim of clarifying long-term OS and causes of death in these patients. We initiated...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6), p.e0127676-e0127676
Hauptverfasser:	Rakotonjanahary, Josué, De Carli, Emilie, Delion, Matthieu, Kalifa, Chantal, Grill, Jacques, Doz, François, Leblond, Pierre, Bertozzi, Anne-Isabelle, Rialland, Xavier
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Antineoplastic Agents - therapeutic use Astrocytoma - drug therapy Astrocytoma - mortality Brain cancer Carboplatin - therapeutic use Chemotherapy Child Child, Preschool Children Cisplatin - therapeutic use Cohort Studies Cyclophosphamide - therapeutic use Death Diagnosis Disease-Free Survival Drug Therapy, Combination Etoposide - therapeutic use Evolution Female France Genetic disorders Glioma Health risk assessment Humans Hypertension Infant Male Medical prognosis Mortality Neurological disorders Oncology Optic Nerve Glioma - drug therapy Optic Nerve Glioma - mortality Osteoprotegerin Patients Pediatrics Procarbazine - therapeutic use Prognosis Radiation therapy Regression analysis Risk analysis Risk factors Surgery Survival Survival Rate Tumors Vincristine - therapeutic use
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