Primary and Chronic HIV Infection Differently Modulates Mucosal Vδ1 and Vδ2 T-Cells Differentiation Profile and Effector Functions

Gut-associated immune system has been identified as a major battlefield during the early phases of HIV infection. γδ T-cells, deeply affected in number and function after HIV infection, are able to act as a first line of defence against invading pathogens by producing antiviral soluble factors and b...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6), p.e0129771-e0129771
Hauptverfasser:	Cimini, Eleonora, Agrati, Chiara, D'Offizi, Gianpiero, Vlassi, Chrysoula, Casetti, Rita, Sacchi, Alessandra, Lionetti, Raffaella, Bordoni, Veronica, Tumino, Nicola, Scognamiglio, Paola, Martini, Federico
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS Blood circulation Cell Differentiation Chemokines Chronic Disease Chronic infection Cytotoxicity Dendritic cells Differentiation Effector cells Exhaustion Female Flow cytometry Gastric cancer HIV HIV Infections - immunology HIV Infections - virology Human immunodeficiency virus Humans Immune system Immunity Immunity, Mucosal Immunology Infections Infectious diseases Laboratories Lymphocyte Activation Lymphocytes Lymphocytes T Male Middle Aged Military technology Mucosal immunity Receptors, Antigen, T-Cell, gamma-delta - immunology Stomach cancer T cell receptors T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - virology γ-Interferon
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