Cell fate reprogramming by control of intracellular network dynamics

Identifying control strategies for biological networks is paramount for practical applications that involve reprogramming a cell's fate, such as disease therapeutics and stem cell reprogramming. Here we develop a novel network control framework that integrates the structural and functional info...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS computational biology 2015-04, Vol.11 (4), p.e1004193-e1004193
Hauptverfasser:	Zañudo, Jorge G T, Albert, Réka
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biology Cell differentiation Cellular Reprogramming - physiology Computational Biology Control theory Experiments Humans Identification and classification Intervention Leukemia Leukemia - physiopathology Models, Biological Physiological aspects Signal transduction Signal Transduction - physiology Standard deviation Stem cells System theory
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!