Recombinant Encephalomyocarditis Viruses Elicit Neutralizing Antibodies against PRRSV and CSFV in Mice

Encephalomyocarditis virus (EMCV) is capable of infecting a wide range of species and the infection can cause myocarditis and reproductive failure in pigs as well as febrile illness in human beings. In this study, we introduced the entire ORF5 of the porcine reproductive and respiratory syndrome vir...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6), p.e0129729-e0129729
Hauptverfasser:	Zhu, Shu, Guo, Xin, Keyes, Lisa R, Yang, Hanchun, Ge, Xinna
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Animal species Animals Antibodies Antibodies, Neutralizing - immunology Antibodies, Viral - immunology Antigenic determinants Antigens Cell Line Classical swine fever virus - immunology Cross Reactions - immunology E2 gene Encephalomyocarditis virus - genetics Encephalomyocarditis virus - immunology Envelope protein Epidemiology Epitopes Fever Gene Expression Genetic engineering Genomes Genomics Glycoproteins Health aspects Heart diseases Hog cholera Hogs Humans Immunization Immunogenicity Immunoglobulins Infection Infections Laboratory animals Livestock Mice Mutation Myocarditis Neutralization Neutralizing Porcine respiratory and reproductive syndrome virus - immunology Protein sorting signals Proteins Recombination, Genetic Reproductive failure Swine Vaccines Veterinary colleges Veterinary medicine Viral envelope proteins Viral infections Viral Proteins - genetics Viral Proteins - immunology Virology Virus Replication Viruses Zoonoses
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