Antibodies against immature virions are not a discriminating factor for dengue disease severity

Humoral immunity plays an important role in controlling dengue virus (DENV) infection. Antibodies (Abs) developed during primary infection protect against subsequent infection with the same dengue serotype, but can enhance disease following secondary infection with a heterologous serotype. A DENV vi...

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Veröffentlicht in:	PLoS neglected tropical diseases 2015-03, Vol.9 (3), p.e0003564
Hauptverfasser:	Rodenhuis-Zybert, Izabela A, da Silva Voorham, Júlia M, Torres, Silvia, van de Pol, Denise, Smit, Jolanda M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Viral - immunology Colleges & universities Dengue - immunology Dengue fever Dengue Virus - immunology Development and progression Experiments Health aspects Humans Immune Sera - immunology Immunoglobulin G - blood Infections Pathogenesis Proteins Viral Envelope Proteins - immunology Virion - immunology
Online-Zugang:	Volltext
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