Proteomics profiling of chikungunya-infected Aedes albopictus C6/36 cells reveal important mosquito cell factors in virus replication

Chikungunya virus (CHIKV) is the only causative agent of CHIKV fever with persistent arthralgia, and in some cases may lead to neurological complications which can be highly fatal, therefore it poses severe health issues in many parts of the world. CHIKV transmission can be mediated via the Aedes al...

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Veröffentlicht in:	PLoS neglected tropical diseases 2015-03, Vol.9 (3), p.e0003544-e0003544
Hauptverfasser:	Lee, Regina Ching Hua, Chu, Justin Jang Hann
Format:	Artikel
Sprache:	eng
Schlagworte:	Aedes - chemistry Aedes - virology Aedes albopictus Animals Arthropoda Cells, Cultured Chikungunya Fever - transmission Chikungunya virus Chikungunya virus - genetics Cricetinae Desorption Electrophoresis, Gel, Two-Dimensional Humans Identification and classification Lasers Male Mass spectrometry Methods Microbiological research Mosquitoes Multienzyme Complexes - physiology Proteomics RNA, Small Interfering - genetics Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Virus Replication - physiology
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