Vaccination with Leishmania infantum acidic ribosomal P0 but not with nucleosomal histones proteins controls Leishmania infantum infection in hamsters

Several intracellular Leishmania antigens have been identified in order to find a potential vaccine capable of conferring long lasting protection against Leishmania infection. Histones and Acid Ribosomal proteins are already known to induce an effective immune response and have successfully been tes...

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Veröffentlicht in:	PLoS neglected tropical diseases 2015-02, Vol.9 (2), p.e0003490-e0003490
Hauptverfasser:	Pereira, Lais, Abbehusen, Melissa, Teixeira, Clarissa, Cunha, Jurema, Nascimento, Ivan P, Fukutani, Kyioshi, dos-Santos, Washington, Barral, Aldina, de Oliveira, Camila Indiani, Barral-Netto, Manoel, Soto, Manoel, Brodskyn, Cláudia Ida
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antibodies, Protozoan - blood Cricetinae Cytokines - biosynthesis Female Hamsters Health aspects Histones - immunology Immune system Leishmania infantum Leishmania infantum - genetics Leishmania infantum - immunology Leishmaniasis Leishmaniasis, Visceral - prevention & control Male Mesocricetus Mice Mortality Parasitic diseases Patient outcomes Prevention Protozoan Vaccines - immunology Ribosomal Proteins - immunology Spleen - immunology Vaccination Vaccines
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