Chagas disease and the london declaration on neglected tropical diseases

  Successes and Advances Among the successes in the control and prevention of Chagas disease is the reduction of vector-based transmission in some countries in the Southern Cone of South America using a combination of widespread and recurrent domestic application of pyrethroid insecticides and scree...

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Veröffentlicht in:PLoS neglected tropical diseases 2014-10, Vol.8 (10), p.e3219-e3219
Hauptverfasser: Tarleton, Rick L, Gürtler, Ricardo E, Urbina, Julio A, Ramsey, Janine, Viotti, Rodolfo
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container_end_page e3219
container_issue 10
container_start_page e3219
container_title PLoS neglected tropical diseases
container_volume 8
creator Tarleton, Rick L
Gürtler, Ricardo E
Urbina, Julio A
Ramsey, Janine
Viotti, Rodolfo
description   Successes and Advances Among the successes in the control and prevention of Chagas disease is the reduction of vector-based transmission in some countries in the Southern Cone of South America using a combination of widespread and recurrent domestic application of pyrethroid insecticides and screening of blood donations to prevent transfusion-related transmission. [...]to long-held views on the autoimmune origin of the pathology of the chronic stage of Chagas disease, multiple lines of investigation confirm that the persistence of parasites is the key factor underlying the sustained inflammatory responses that lead to such manifestations [8], [9]. [...]the condition should be treated as an infectious, not an autoimmune, disease, and specific treatment should be offered to all seropositive patients, perhaps with the exception of those with terminal disease [2], [10].
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subjects Biology and Life Sciences
Chagas' disease
Control
Infection control
Laws, regulations and rules
Medicine and Health Sciences
Parasitic diseases
Pharmaceutical industry
Planning
Policy Platform
Prevention
Protozoa
Science Policy
Tropical diseases
Vaccines
title Chagas disease and the london declaration on neglected tropical diseases
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