Identification of HNRNPK as regulator of hepatitis C virus particle production

Hepatitis C virus (HCV) is a major cause of chronic liver disease affecting around 130 million people worldwide. While great progress has been made to define the principle steps of the viral life cycle, detailed knowledge how HCV interacts with its host cells is still limited. To overcome this limit...

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Veröffentlicht in:	PLoS pathogens 2015-01, Vol.11 (1), p.e1004573-e1004573
Hauptverfasser:	Poenisch, Marion, Metz, Philippe, Blankenburg, Hagen, Ruggieri, Alessia, Lee, Ji-Young, Rupp, Daniel, Rebhan, Ilka, Diederich, Kathrin, Kaderali, Lars, Domingues, Francisco S, Albrecht, Mario, Lohmann, Volker, Erfle, Holger, Bartenschlager, Ralf
Format:	Artikel
Sprache:	eng
Schlagworte:	Atoms & subatomic particles Biology and Life Sciences Cells, Cultured Genomes Health aspects HEK293 Cells Hepacivirus - drug effects Hepacivirus - physiology Hepatitis Hepatitis C virus Heterogeneous-Nuclear Ribonucleoprotein K Host-virus relationships Humans Identification and classification Libraries Lipids Liver diseases Medicine and Health Sciences Protein Binding Proteins Ribonucleoproteins Ribonucleoproteins - antagonists & inhibitors Ribonucleoproteins - physiology RNA Interference RNA, Small Interfering - pharmacology RNA, Viral - metabolism Viral proteins Virion - drug effects Virion - physiology Virus Assembly - drug effects Virus Assembly - genetics Virus Replication - drug effects Virus Replication - genetics Viruses
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