Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection

Urinary tract infections (UTIs) afflict over 9 million women in America every year, often necessitating long-term prophylactic antibiotics. One risk factor for UTI is frequent sexual intercourse, which dramatically increases the risk of UTI. The mechanism behind this increased risk is unknown; howev...

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Veröffentlicht in:	PLoS pathogens 2015-01, Vol.11 (1), p.e1004599-e1004599
Hauptverfasser:	Schwartz, Drew J, Conover, Matt S, Hannan, Thomas J, Hultgren, Scott J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics Bacteria Biology and Life Sciences Bladder Bladder diseases Cystitis - complications Cystitis - microbiology Cystitis - pathology Cytokines Development and progression Disease Models, Animal Disease Progression E coli Escherichia coli Escherichia coli Infections - complications Escherichia coli Infections - pathology Experiments Female Health aspects Host-bacteria relationships Identification and classification Infections Laboratory animals Medicine and Health Sciences Mice Mice, Inbred C3H Mice, Inbred C57BL Scanning electron microscopy Severity of Illness Index Statistical analysis Superinfection - complications Superinfection - pathology Urinary Bladder - microbiology Urinary Bladder - pathology Urinary tract diseases Urinary Tract Infections - complications Urinary Tract Infections - pathology Urine Urogenital system Urology Uropathogenic Escherichia coli - pathogenicity Uropathogenic Escherichia coli - physiology Women
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