A novel alpha kinase EhAK1 phosphorylates actin and regulates phagocytosis in Entamoeba histolytica

Phagocytosis plays a key role in nutrient uptake and virulence of the protist parasite Entamoeba histolytica. Phagosomes have been characterized by proteomics, and their maturation in the cells has been studied. However, there is so far not much understanding about initiation of phagocytosis and for...

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Veröffentlicht in:	PLoS pathogens 2014-10, Vol.10 (10), p.e1004411-e1004411
Hauptverfasser:	Mansuri, M Shahid, Bhattacharya, Sudha, Bhattacharya, Alok
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Biology and Life Sciences Calcium-Binding Proteins - metabolism Cell Membrane - metabolism Clergy Entamoeba histolytica Entamoeba histolytica - enzymology Entamoeba histolytica - genetics Erythrocytes - parasitology Health aspects Kinases Mammals Mice Microbiological research Musculoskeletal system Phagocytosis - physiology Phagosomes - metabolism Phosphorylation Phosphotransferases Protein Kinases - metabolism Protein-Serine-Threonine Kinases - metabolism Proteins Proteomics Protozoan Proteins - metabolism Signal transduction Software
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