Enhancement of early cervical cancer diagnosis with epithelial layer analysis of fluorescence lifetime images

This work reports the use of layer analysis to aid the fluorescence lifetime diagnosis of cervical intraepithelial neoplasia (CIN) from H&E stained cervical tissue sections. The mean and standard deviation of lifetimes in single region of interest (ROI) of cervical epithelium were previously sho...

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Veröffentlicht in:	PloS one 2015-05, Vol.10 (5), p.e0125706-e0125706
Hauptverfasser:	Gu, Jun, Fu, Chit Yaw, Ng, Beng Koon, Liu, Lin Bo, Lim-Tan, Soo Kim, Lee, Caroline Guat Lay
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cancer diagnosis Cervical cancer Cervical Intraepithelial Neoplasia - pathology Cervix Diagnosis Early Detection of Cancer - methods Engineering Epithelial cells Epithelium Female Fluorescence Handbooks Health sciences Human papillomavirus Humans Image Interpretation, Computer-Assisted - methods Learning algorithms Lifetime Medical diagnosis Medical screening Microscopy, Fluorescence - methods Morphology Neural networks Pathology Photonics Sensitivity analysis Sensitivity and Specificity Uterine Cervical Neoplasms - pathology Womens health
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