Multi-pathway cellular analysis on crude natural drugs/herbs from Japanese Kampo formulations

Kampo formulations comprise a number of crude natural drugs/herbs as constituents. The crude drugs/herbs have been traditionally classified by their traditional classifications or efficacies in Kampo medicines; however, it has been difficult to establish the scientific link between experimental evid...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6), p.e0128872-e0128872
Hauptverfasser:	Eshima, Shizuka, Yokoyama, Satoru, Abe, Takashi, Hayakawa, Yoshihiro, Saiki, Ikuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Biochemistry Cell Line, Tumor Cellular signal transduction Cluster Analysis Clustering Correlation analysis Correlation coefficient Correlation coefficients Cyclic AMP response element-binding protein Drugs Drying Experiments Formulations Gene expression Genes, Reporter Health aspects Herbs Humans Intracellular signalling LEF protein Lung cancer Lung diseases Medicinal plants Medicine Medicine, Kampo Moisture content Myc protein NF-κB protein p53 Protein Plant Extracts - isolation & purification Plant Extracts - pharmacology Plants, Medicinal - chemistry Plasmids Signal Transduction - drug effects Smad protein Traditional medicine Transcription Transcription factors Transcription, Genetic - drug effects
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